4ĭiagnostic practices vary widely even among specialists primarily because of lack of consensus criteria in diagnosing adolescents with PCOS. These features include anovulatory menstrual cycles, transient multi-follicular ovarian morphology that may appear polycystic by ultrasound, increased androgen effects, and relative insulin resistance secondary to increased growth hormone levels. ![]() ![]() 2,3 It is challenging to make a diagnosis during the 1–2 years following menarche because normal pubertal changes can mimic features of PCOS. 1 However, PCOS is likely underdiagnosed, especially in adolescent patients. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in adolescent and adult women, and importantly has both reproductive and metabolic consequences. ![]() DiVasta is an assistant professor of pediatrics at Harvard Medical School, Boston, Massachusetts.
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